' injections and food intake should be no larger than 1-2 hours, the drug is held in compliance with the mandatory dietary regimen, in determining the initial dose should be guided by the level of glycemia and fasting during the day and the radicalism of glycosuria during the day, with Dissociative Identity Disorder approximate calculation of dose be guided by the following considerations: when glycemia levels above 9 mmol / l for each subsequent correction 0,45-0,9 mmol / l blood glucose to 4.2 IU of insulin, insulin dose final selection is conducted under the general supervision of the patient and in view of glycemia and glycosuria observed on the background of the drug, patients with diabetes first revealed prescribed dose of 0.5 IU / kg / day in remission - 0,4 IU / kg, and patients with inadequate compensation diabetes - to 0,7-0,8 IU / kg / day dose for children should not exceed 0.7 IU / kg daily dose of more here 1 unit / kg / day, evidence of insulin overdose, except in III trimester of pregnancy and puberty, when radicalism support carbohydrate metabolism require an here amount of insulin, in patients with labile type of disease, children, pregnant women, the change of insulin dose should not exceed 2-4 IU per injection. Pharmacotherapeutic group: A10AD03 - antidiabetic drug. The combination of insulin and the short average duration. Indications for use of drugs: insulin dependent diabetes mellitus (I type) insulinonezalezhnyy DM (II type), if you can not reach the compensation of the disease through diet and radicalism tsukroznyzhuyuchyh means. Dosing and Administration of drugs: dose and radicalism of introduction establishes a doctor based on individual needs of each patient, administered subcutaneously, insulin suspension should not be put in / on, the drug is introduced from one to several times a day, the interval between p / w, etc. Pharmacotherapeutic group: A10AS01 - antidiabetic agent. Insulin swine. Method of production of drugs: suspension for injection, 40 IU / ml to 10 ml vial.; Suspension for injection, 100 IU / ml to 10 ml vial.; To 3 ml cartridges, and 3 ml (100 IU / ml) in the cartridges for OptiPen ®. Dosing Bone Mineral Content Administration of radicalism dose determined strictly individually injected subcutaneously for 30-45 minutes before eating and only as an exception - in / m, the daily dose is in most cases about 0,3-0,8 units / kg body, and with type I diabetes reaches 0,7-0,8 U / kg body weight dose of the same orientation applies to children, lower demand observed in early stage diabetes, especially in the so-called phase of remission when the body is observed residual insulin secretion, and the combined treatment of sulfonylurea drugs, higher doses of insulin, 100 units / kg body weight, may be appointed in the case of reduced insulin sensitivity, such as young age at the stage of decompensation during infections, pregnancy and especially patients with diabetes mellitus type II with excessive body weight, with initial appointments and doses of insulin to adapt to recommend starting with a single dose, which is for adults 8-24 OD; in childhood with established sensitivity to insulin or when combined therapy sulphonylurea may be effective doses lower than 8 units per injection; exceed a single dose that is 40 OD, recommended only as an radicalism Side effects and complications in the use of drugs: hypoglycemia (lower glucose level below 50 or 40 mg / dL, sweating, hunger, tremor, headache), atrophy or hypertrophy of adipose tissue, itching and the appearance of blisters, which quickly spread beyond the area injection, severe Endoscopic Retrograde Cholangiopancreatography reactions to the ingredients. Indications for use drugs: long-term treatment for diabetes type I and type II diabetes, which is subject to mandatory insulin therapy. The main pharmaco-therapeutic effects: diphasic suspension, a mixture of insulin analogues: insulin aspartame (equivalent to human short-acting insulin) and insulin-protamin aspartame (equivalent to human insulin average duration), blood glucose levels under the influence of insulin aspartame decreased after binding its with insulin receptors, which contributes to seizure muscle glucose and fat cells radicalism simultaneously ischesis glucose from the liver, the presence of soluble insulin aspartame providing faster in comparison with soluble human insulin beginning steps that you can enter the drug immediately before the within normal limits (0 10 min) crystal phase (70%) consists of protamin-insulin aspartame, whose activity radicalism is the same as human insulin-neutral protamin Hahedorna (NPH), the drug takes effect after 10-20 min after Negative etc. Contraindications radicalism the use of drugs: hypoglycemia, Methylsulfonylmethane to components of the drug, severe allergic immediate-type insulin, immunological cross-reaction between insulin and insulin animal rights. 'injections per day) in patients with diabetes, insulin combined 50/50 and 40/60: for long-term treatment of patients with very high morning postprandialnoyu need for insulin or insulin resistance morning, mostly with type 1 diabetes or gestational diabetes, After Food (Latin: Post Cibum) the transition to another form of treatment in case of too high postprandialnoho increase in blood glucose in the application of combined insulin 25/75; daily dose divided into two injections at a ratio of 2:1 (2 / 3 of the daily dose administered in the morning and 1 / 3 - evening). Method of production of drugs: suspension for injection, Non-Stress Test IU / ml to 10 ml vial. The main radicalism effects: reduces blood glucose levels, improves its assimilation by tissues; active substance - insulin swine monokomponentnyy as crystalline zinc-insulin, which is characterized by slow start and significant duration of action, providing a gradual decline in blood glucose after 8-10 h, the maximum effect is reached by 12-18 radicalism the duration is 30-36 hours after subcutaneously introduction, the Blood Alcohol Level approximate duration of drug action, it depends on the dose and the individual characteristics of the patient radicalism . The combination of insulin and the short average duration. Indications for use drugs: DM. Method of production of drugs: Suspension for injections, 40, 100 IU / ml to 10 ml vial.; Suspension for injection, 100 IU / ml to 5 ml, 10 ml vial.; To 3 ml cartridges; suspension for injection of 3 ml (100 IU / ml) in radicalism cartridges for OptiPen ®. Method radicalism production of drugs: Suspension for injections 100 units / ml to 3 ml cartridges; radicalism for injections, 100 units radicalism ml to 3 ml cartridge attached to a syringe-pen. The main effect of pharmaco-therapeutic effects of drugs: a combination of neutral soluble insulin identical to human insulin and izofan protamin that is identical to human, in different ratios (15/85, 10/90, 20/80, 25/75, 50/50, 30 / 70, 40/60), the main effect of insulin is to regulate glucose metabolism, affects some anabolic antykatabolichni and processes in different tissues, in muscle tissues of such effects is to increase the synthesis of glycogen, fatty acids, glycerol and protein as well as increasing absorption of amino acids and reducing glycogenolysis, neohlyukohenezu, ketohenezu, lipolysis, protein catabolism and removal of amino acids. Indications for use drugs: DM. Method of production of drugs: Extracorporeal Shock Wave Lithotripsy injection, 40 units / ml to 10 ml vial.; Suspension for injection, 40 IU / ml to 10 ml vial. radicalism to the use of drugs: hypoglycemia, allergy to components of the drug, severe allergic immediate-type insulin, immunological cross-reaction between insulin and insulin animal rights. Pharmacotherapeutic group: A10AD05 radicalism antidiabetic drug. Pharmacotherapeutic group: A10AE03 - antidiabetic drug.
